Alcohol Biomarkers: Phosphatidylethanol

Next-Generation Biomarker Testing

PEth-POINT: point-of-care testing for objective alcohol

Lifespan Technologies is developing next-generation PEth testing tools to support objective detection of alcohol exposure.

Our work includes a rapid lateral flow immunoassay for PEth detection and dried blood spot cards containing whole blood with known amounts of PEth. Together, these tools are designed to help expand access to practical alcohol biomarker testing for pre-clinical, research, and public health use.

A New Approach to PEth Detection

PEth forms in red blood cell membranes when ethanol is present. Because it can remain detectable for weeks, PEth offers a meaningful window into alcohol exposure beyond traditional short-term markers.

Lifespan’s technology aims to make PEth detection more accessible while preserving the reliability needed for serious research and clinical applications.

Rapid Lateral Flow Immunoassay

Point-of-Care Format

The Lifespan PEth LFIA is being developed as a rapid, easy-to-use lateral flow format.

Features

    • Visible PEth detection

    • Rapid format

    • Designed for clinical and research settings

    • Supports timely, objective assessment

Key Advantages

    • Faster workflow

    • Point-of-care potential

    • Objective alcohol exposure information

    • Weeks-long detection window

Dried Blood Spot Cards

Convenient PEth Materials

Lifespan is developing dried blood spot cards with five spots and whole blood containing known amounts of PEth. We are developing at least three primary DBS card formats: 

(I) 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanol (POPEth, PEth (16:0/18:1),

(II) Deuterated D5-POPEth, and

(III) Naturally formed PEth– that contains multiple PEth species.

Dried blood-spot card

These materials are intended to provide convenient, useful tools for PEth assay development and research workflows. Products are Research Use Only (RUO). Not approved for human diagnostic use.

Visit Lifespan at RSA 2026

June 20–24 | San Antonio, Texas

Meet with Lifespan Technologies at RSA 2026 to learn how we are transforming alcohol biomarker detection with next-generation PEth testing.

For more information, please call or text at 801.971.1818, fill out the Lifespan Technical Service Form, or email info@lifespantech.com.

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